On the night of Cameron Levy's 40th birthday, three female co-workers, who were pushed too far by his male-chauvinism, decide to have a little fun at his expense.

 

Cameron, a senior exec at a Boston film studio, becomes the victim of a Hoodoo curse which slowly morphs him into a woman after each condescending remark he makes towards the opposite sex.

 

​He must now travel on his best behavior to New Orleans (during Mardi Gras, no less) before it gets any worse and attempt to reverse the spell, then rush back home for his --or her-- crucial meeting with a best-selling, Young-Adult author.